Исследование по изучению CSL112 у субъектов с острым коронарным синдромом
Название протокола
Клинические исследование Острый коронарный синдром: Apolipoprotein A-I [human] (apoA-I), Плацебо - Реестр клинических исследований
Платное
Нет
Дата начала и окончания КИ
2022-02-06 - 2022-02-06
Спонсоры
Ведущий спонсор:
CSL Behring
Источник
CSL Behring
Краткое содержание
Это фаза 3, многоцентровая, двойная слепая, рандомизированная, плацебо-контролируемая, параллельная группа. исследование для оценки эффективности и безопасности CSL112 в отношении снижения неблагоприятных сердечно-сосудистых заболеваний. события [MACE - смерть от сердечно-сосудистых заболеваний (ССЗ), инфаркт миокарда (ИМ) и инсульт] у субъектов с острым коронарным синдромом (ОКС) с диагнозом миокард с подъемом сегмента ST инфаркт миокарда (ИМпST) или инфаркт миокарда без подъема сегмента ST (ИМпST), включая те, которым удалось провести чрескожное коронарное вмешательство (ЧКВ) или лечить с медицинской точки зрения.
Общий статус
Рекрутинг
Дата начала
2018-03-21
Дата завершения
2023-04-01
Дата первичного завершения
2022-07-01
Фаза
Фаза 3
Тип исследования
Интервенционный
Первичный результат
Мера
Временное ограничение
Время до первого появления любого компонента комбинированного MACE (смерть от сердечно-сосудистых заболеваний, инфаркт миокарда или инсульт)
Через 90 дней
Вторичный результат
Мера
Временное ограничение
Key secondary outcome: Total number of hospitalizations for coronary, cerebral, or peripheral ischemia
Through 90 days
Ключевой вторичный результат: время до первого появления смерти от сердечно-сосудистых заболеваний, инфаркта миокарда или инсульта.
Через 180 дней
Ключевой вторичный результат: время до первого появления смерти от сердечно-сосудистых заболеваний, инфаркта миокарда или инсульта.
Через 365 дней
Время до наступления смерти от ССЗ
Через 90 дней
Время до первого появления ИМ
Через 90 дней
Время до первого инсульта
Через 90 дней
Время до наступления смерти по любой причине
Через 365 дней
Количество субъектов с нежелательными явлениями
Через 90 дней
Процент субъектов с нежелательными явлениями
Через 90 дней
Количество субъектов с побочными эффектами, связанными с лечением
Через 365 дней
Процент субъектов с побочными эффектами, связанными с лечением
Через 365 дней
Количество субъектов с серьезными нежелательными явлениями
Через 365 дней
Процент субъектов с серьезными нежелательными явлениями
Через 365 дней
Количество субъектов со сдвигом в клинических лабораторных оценках от исходного уровня до наихудшего значения после лечения в соответствии с критериями нормального диапазона (нормальный, высокий или низкий)
Исходный уровень и 29 дней
Процент субъектов со сдвигом в клинических лабораторных оценках от исходного уровня до наихудшего значения после лечения в соответствии с критериями нормального диапазона (нормальный, высокий или низкий)
Исходный уровень и 29 дней
Регистрация
17400
Состояние
Острый коронарный синдром
Вмешательство
Тип вмешательства:
Biological
Название вмешательства:
Apolipoprotein A-I [human] (apoA-I)
Описание:
Apolipoprotein A-I [human] (apoA-I) purified from human plasma for intravenous administration
Этикетка Arm Group:
CSL112
Другое имя:
CSL112
Тип вмешательства:
Другой
Название вмешательства:
Плацебо
Описание:
25% раствор альбумина, разбавленный до 4,4%
Этикетка Arm Group:
Плацебо
Приемлемость
Критерии:
Критерии включения: - Мужчина или женщина моложе 18 лет - Признаки некроза миокарда, соответствующие ИМ I типа (спонтанный). - Нет подозрений на острое повреждение почек - Доказательства многососудистой ишемической болезни сердца - Наличие факторов риска сердечно-сосудистых заболеваний: 1. Сахарный диабет на фармакотерапии ИЛИ. 2. 2 или более из следующего: возраст ≥ 65 лет, перенесенный инфаркт миокарда в анамнезе, периферический артериальное заболевание Критерий исключения: - Постоянная гемодинамическая нестабильность. - Доказательства гепатобилиарной болезни - Доказательства тяжелой хронической болезни почек - Запланируйте плановую операцию по аортокоронарному шунтированию в качестве лечения индекс MI - Известная история аллергии, гиперчувствительности или дефицита сои, арахиса или альбумин
Пол:
Все
Минимальный возраст:
18 лет
Максимальный возраст:
N / A
Здоровые волонтеры:
Нет
Общий Официальный
Фамилия
Роль
Присоединение
Danielle Duffy, MD
Study Director
CSL Behring - Sr Global Clinical Program Dir - CV & Metabolism
Общий контакт
Фамилия:
Trial Registration Coordinator
Телефон:
610-878-4000
Расположение
Объект:
Положение дел:
Контакт:
8400896 - Advanced Cardiovascular LLC
| Alexander City, Alabama, 35010, United States
Recruiting
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8400350 - Cardiology, PC
| Birmingham, Alabama, 35211, United States
Recruiting
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8400337 - Heart Center Research, LLC
| Huntsville, Alabama, 35801, United States
Recruiting
8400713 - University of South Alabama College of Medicine
| Mobile, Alabama, 36617, United States
Active, not recruiting
8400556 - Mercy Gilbert Medical Center
| Gilbert, Arizona, 85297, United States
Recruiting
Use Central Contact
8400747 - Phoenix V.A. Health Care System
| Phoenix, Arizona, 85012, United States
Completed
8400772 - Mayo Clinic Arizona
| Phoenix, Arizona, 85054, United States
Active, not recruiting
8400996 - Southern Arizona V.A. Healthcare System
| Tucson, Arizona, 85723, United States
Recruiting
Use Central Contact
8400789 - Sparks Regional Medical Center
| Fort Smith, Arkansas, 72901, United States
Active, not recruiting
8400645 - NEA Baptist Clinic
| Jonesboro, Arkansas, 72401, United States
Recruiting
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8400975 - Central Arkansas Veterans Healthcare System
| Little Rock, Arkansas, 72205, United States
Recruiting
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8401054 - Central Cardiology Medical Center
| Bakersfield, California, 93308, United States
Active, not recruiting
8400379 - John Muir Health and Cardiovascular Institute
| Concord, California, 94520, United States
Recruiting
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8400931 - Valley Clinical Trials
| Covina, California, 91723, United States
Recruiting
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8401103 - Orange Coast Memorial Hospital
| Fountain Valley, California, 92708, United States
Recruiting
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8401166 - Sharp Grossmont Hospital
| La Mesa, California, 91942, United States
Recruiting
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8401192 - South Orange County Surgical Medical Group
| Laguna Hills, California, 92653, United States
Recruiting
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8400596 - Long Beach Memorial Medical Center
| Long Beach, California, 90806, United States
Recruiting
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8400910 - Cardiovascular Innovation and Research Center
| Long Beach, California, 90813, United States
Active, not recruiting
8400597 - Los Alamitos Cardiovascular
| Los Alamitos, California, 90720, United States
Recruiting
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8400693 - University of California Los Angeles
| Los Angeles, California, 90038, United States
Recruiting
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8400717 - V.A. Greater Los Angeles Healthcare System
| Los Angeles, California, 90073, United States
Recruiting
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8400888 - Saint Jude Heritage Healthcare
| Mission Viejo, California, 92691, United States
Recruiting
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8400745 - Hoag Memorial Hospital Presbyterian
| Newport Beach, California, 92663, United States
Recruiting
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8400658 - Valley Clinical Trials, Inc.
| Northridge, California, 91325, United States
Recruiting
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8400720 - Valley Clinical Trials
| Pasadena, California, 91105, United States
Recruiting
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8400787 - Riverside Community Hospital
| Riverside, California, 92501, United States
Active, not recruiting
8400694 - University of California San Diego Medical Center
| San Diego, California, 92103, United States
Active, not recruiting
8400703 - San Diego Cardiac Center
| San Diego, California, 92123, United States
Recruiting
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8400719 - V.A. San Diego Health Care System
| San Diego, California, 92161, United States
Recruiting
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8400909 - Ventura Clinical Trials
| Ventura, California, 93003, United States
Recruiting
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8400891 - John Muir Medical Center Walnu
| Walnut Creek, California, 94598, United States
Recruiting
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8400893 - Interventional Cardiology Medical Group
| West Hills, California, 91307, United States
Recruiting
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8400574 - Aurora Denver Cardiology Associates
| Aurora, Colorado, 80012, United States
Recruiting
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8400684 - UCHealth Memorial Hospital Central - Colorado Springs
| Colorado Springs, Colorado, 80909, United States
Completed
8400997 - CardioVascular Institute of North Colorado Cardiology Clinic
| Greeley, Colorado, 80631, United States
Recruiting
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8400670 - Medical Center of the Rockies
| Loveland, Colorado, 80538, United States
Completed
8400371 - Danbury Hospital
| Danbury, Connecticut, 06810, United States
Recruiting
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8401134 - Christiana Hospital
| Newark, Delaware, 19718, United States
Recruiting
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8400779 - MedStar Clinical Research Center
| Washington, District of Columbia, 20010, United States
Recruiting
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8400688 - George Washington University Medical Center
| Washington, District of Columbia, 20037, United States
Recruiting
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8400484 - Clearwater Cardiovascular and Interventional Consultants
| Clearwater, Florida, 33756, United States
Recruiting
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8400544 - Cardiology Research Associates
| Daytona Beach, Florida, 32117, United States
Recruiting
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8400930 - Lake Internal Medicine Assoc.
| Eustis, Florida, 32726, United States
Completed
8400613 - Jim Moran Heart and Vascular Center
| Fort Lauderdale, Florida, 33308, United States
Recruiting
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8401010 - Integrative Research Associates Inc.
| Fort Lauderdale, Florida, 33312, United States
Recruiting
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8400490 - University of Florida
| Gainesville, Florida, 32610, United States
Recruiting
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8400517 - Shands Jacksonville Medical Center
| Jacksonville, Florida, 32209, United States
Recruiting
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8400985 - Optimus U Corp.
| Miami, Florida, 33125, United States
Completed
8400543 - Cardiology Partners Research Institute
| Palm Beach Gardens, Florida, 33410, United States
Recruiting
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8400542 - Cardiology Consultants
| Pensacola, Florida, 32501, United States
Recruiting
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8400557 - Clearwater Cardiovascular and Interventional Consultants
| Safety Harbor, Florida, 34695, United States
Recruiting
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8400686 - Intercoastal Medical Group
| Sarasota, Florida, 34239, United States
Recruiting
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8400736 - Pepin Heart Institute
| Tampa, Florida, 33613, United States
Recruiting
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8401011 - Cardiology Partners Research Institute
| Wellington, Florida, 33449, United States
Completed
8401185 - Piedmont Heart Institute
| Athens, Georgia, 30606, United States
Active, not recruiting
8400376 - Emory University
| Atlanta, Georgia, 30322-1059, United States
Recruiting
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8400918 - Augusta University
| Augusta, Georgia, 30912, United States
Recruiting
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8400849 - IACT Health
| Columbus, Georgia, 31904, United States
Recruiting
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8400655 - Atlanta V.A. Medical Center
| Decatur, Georgia, 30033, United States
Recruiting
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8401120 - Northeast Georgia Medical Center
| Gainesville, Georgia, 30501, United States
Recruiting
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8401157 - Memorial Health University Medical Center
| Savannah, Georgia, 31404, United States
Recruiting
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8400357 - Saint Luke's Boise Medical Center
| Boise, Idaho, 83712, United States
Recruiting
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8400610 - Jesse Brown V.A. Medical Center
| Chicago, Illinois, 60612, United States
Recruiting
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8401093 - Advanced Heart Care Group
| Fairview Heights, Illinois, 62208, United States
Recruiting
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8401000 - Advocate Lutheran General Hospital
| Park Ridge, Illinois, 60068, United States
Recruiting
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8400785 - OSF Multi-Specialty Group
| Peoria, Illinois, 61614, United States
Recruiting
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8400361 - Midwest Cardiovascular Research
| Elkhart, Indiana, 46514, United States
Recruiting
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8400961 - Indiana Heart Physicians, Inc.
| Indianapolis, Indiana, 46237, United States
Recruiting
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8400989 - Indiana Heart Hospital
| Indianapolis, Indiana, 46250, United States
Recruiting
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8400507 - The Saint Vincent Heart Center of Indiana
| Indianapolis, Indiana, 46290, United States
Recruiting
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8400576 - IU Health Ball Memorial Hospital Physicians, Inc
| Muncie, Indiana, 47303, United States
Recruiting
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8400882 - Reid Health
| Richmond, Indiana, 47374, United States
Recruiting
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8400618 - McFarland Clinic, PC
| Ames, Iowa, 50010, United States
Completed
8400904 - Northeast Iowa Medical Education Foundation
| Waterloo, Iowa, 50702, United States
Recruiting
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8400678 - The Iowa Clinic, PC
| West Des Moines, Iowa, 50266, United States
Completed
8400978 - Midwest Heart and Vascular
| Overland Park, Kansas, 66209, United States
Completed
8400661 - Norton Cardiovascular Associates
| Louisville, Kentucky, 40205, United States
Recruiting
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8400368 - Cambridge Medical Trials
| Alexandria, Louisiana, 71301, United States
Recruiting
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8400862 - Cardiovascular Associates Research
| Covington, Louisiana, 70433, United States
Recruiting
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8401104 - Cardiovascular Institute of the South
| Houma, Louisiana, 70361-4176, United States
Recruiting
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8400563 - Cardiovascular Institute of the South
| Lafayette, Louisiana, 70503, United States
Recruiting
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8401127 - Tulane University Health Science Center
| New Orleans, Louisiana, 70112, United States
Recruiting
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8401173 - Ochsner Clinic Foundation
| New Orleans, Louisiana, 70121, United States
Recruiting
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8401175 - Overton Brooks V.A. Medical Center
| Shreveport, Louisiana, 71101, United States
Active, not recruiting
8400483 - Eastern Maine Medical Center
| Bangor, Maine, 04401, United States
Recruiting
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8400812 - Maine Medical Center Bramhall Campus
| Portland, Maine, 04102, United States
Recruiting
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8401142 - Anne Arundel Health System
| Annapolis, Maryland, 21401, United States
Completed
8401163 - Washington Adventist Hospital
| Takoma Park, Maryland, 20912, United States
Recruiting
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8400998 - Beth Israel Deaconess Medical Center
| Boston, Massachusetts, 02215, United States
Recruiting
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8400769 - Healthy Heart Cardiology
| Grandville, Michigan, 49418, United States
Recruiting
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8401141 - Western Michigan University Homer Striker MD School of Medicine
| Kalamazoo, Michigan, 49048, United States
Recruiting
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8400638 - Mid Michigan Regional Medical Center
| Midland, Michigan, 48670, United States
Recruiting
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8401092 - Saint Joseph Mercy Oakland
| Pontiac, Michigan, 48341, United States
Recruiting
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8400861 - Ascension Providence Rochester Hospital
| Rochester, Michigan, 48307, United States
Recruiting
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8400372 - Covenant Medical Center
| Saginaw, Michigan, 48602, United States
Recruiting
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8400667 - Michigan Cardiovascular Institute
| Saginaw, Michigan, 48602, United States
Completed
8401165 - Ascension Macomb-Oakland Hospital Warren Campus
| Warren, Michigan, 48236, United States
Recruiting
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8400625 - Michigan Heart and Vascular Institute
| Ypsilanti, Michigan, 48197, United States
Recruiting
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8400488 - Essentia Health
| Duluth, Minnesota, 55805, United States
Completed
8400920 - Saint Lukes Hospital
| Duluth, Minnesota, 55805, United States
Recruiting
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8400364 - Minneapolis Heart Institute Foundation
| Minneapolis, Minnesota, 55401, United States
Recruiting
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8400752 - Regions Hospital
| Saint Paul, Minnesota, 55101, United States
Recruiting
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8400369 - HealthEast Saint Joseph's Hospital
| Saint Paul, Minnesota, 55102, United States
Completed
8401168 - Jackson Heart Clinic
| Jackson, Mississippi, 39216, United States
Recruiting
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8400334 - Cardiology Associates of North Mississippi
| Tupelo, Mississippi, 38801, United States
Recruiting
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8401108 - University of Missouri Health System
| Columbia, Missouri, 65212, United States
Recruiting
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8400648 - Saint Luke's Cardiovascular Consultants
| Kansas City, Missouri, 64111, United States
Completed
8400631 - North Kansas City Hospital
| North Kansas City, Missouri, 64116, United States
Recruiting
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8400840 - Washington University
| Saint Louis, Missouri, 63110, United States
Recruiting
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8400622 - Mercy Medical Research Institute
| Springfield, Missouri, 65807, United States
Active, not recruiting
8400091 - Glacier View Cardiology
| Kalispell, Montana, 59901, United States
Recruiting
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8400783 - Nebraska Heart Institute
| Lincoln, Nebraska, 68526, United States
Recruiting
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8400689 - University Medical Center
| Las Vegas, Nevada, 89102, United States
Recruiting
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8400545 - Advanced Heart Care LLC
| Bridgewater, New Jersey, 08807, United States
Recruiting
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8400835 - Cooper University Hospital
| Camden, New Jersey, 08103, United States
Recruiting
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8400836 - Our Lady of Lourdes Medical Center
| Camden, New Jersey, 08103, United States
Recruiting
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8401178 - Jersey Shore University Medical Center Meridian Health
| Neptune, New Jersey, 07753, United States
Recruiting
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8401144 - Saint Michael's Medical Center
| Newark, New Jersey, 07102, United States
Recruiting
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8400572 - AtlantiCare Regional Medical Center
| Pomona, New Jersey, 08240, United States
Recruiting
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8401189 - Cardiovascular Associates of the Delaware Valley
| Vineland, New Jersey, 08360, United States
Recruiting
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8400742 - VMG Cardiology, Westwood
| Westwood, New Jersey, 07675, United States
Recruiting
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8400626 - Montefiore Medical Center - Albert Einstein College of Medicine
| Bronx, New York, 10461, United States
Recruiting
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8400636 - Jacobi Medical Center
| Bronx, New York, 10461, United States
Recruiting
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8400360 - Buffalo Heart Group
| Buffalo, New York, 14215, United States
Recruiting
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8401028 - Buffalo V.A. Medical Center
| Buffalo, New York, 14215, United States
Completed
8400677 - Saint Joseph's Hospital Cardiac Catheterization Associates
| Liverpool, New York, 13088, United States
Recruiting
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8400380 - Mount Sinai Medical Center
| New York, New York, 10029, United States
Recruiting
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8401119 - Lenox Hill Hospital
| New York, New York, 10075, United States
Recruiting
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8401154 - Rochester General Hospital
| Rochester, New York, 14621, United States
Completed
8400847 - University of Rochester Medical Center-Strong Memorial Hospital
| Rochester, New York, 14642, United States
Completed
8400726 - Westchester Medical Center
| Valhalla, New York, 10595, United States
Recruiting
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8401027 - UNC Hospitals Heart and Vascular Center at Meadowmont
| Chapel Hill, North Carolina, 27517, United States
Recruiting
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8400733 - Novant Health Heart and Vascular Institute
| Charlotte, North Carolina, 28204, United States
Completed
8400489 - Duke University Hospital
| Durham, North Carolina, 27710, United States
Active, not recruiting
8400491 - Moses H. Cone Memorial Hospital
| Greensboro, North Carolina, 27401-1020, United States
Recruiting
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8400366 - High Point Regional Hospital
| High Point, North Carolina, 27262, United States
Recruiting
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8400916 - Southeastern Cardiology & Cardiovascular Clinic
| Lumberton, North Carolina, 28358, United States
Recruiting
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8400887 - Matthews Medical Center
| Matthews, North Carolina, 28105, United States
Completed
8400889 - NC Heart and Vascular Research
| Raleigh, North Carolina, 27607, United States
Completed
8400322 - Wake Forest University Health Sciences, Dept. of Cardiovascular Medicine
| Winston-Salem, North Carolina, 27157, United States
Recruiting
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8400651 - Sanford Medical Center Fargo
| Fargo, North Dakota, 58122, United States
Completed
8400682 - Trinity Medical Group
| Minot, North Dakota, 58701, United States
Recruiting
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8400657 - Summa Health
| Akron, Ohio, 44304, United States
Recruiting
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8400793 - Aultman Hospital
| Canton, Ohio, 44710, United States
Recruiting
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8400858 - University of Cincinnati
| Cincinnati, Ohio, 45219, United States
Recruiting
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8401233 - Cincinnati V.A. Medical Center
| Cincinnati, Ohio, 45220, United States
Recruiting
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8400966 - MetroHealth System
| Cleveland, Ohio, 44109, United States
Recruiting
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8400565 - Miami Valley Hospital
| Dayton, Ohio, 45409, United States
Recruiting
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8400654 - North Ohio Research Ltd.
| Elyria, Ohio, 44035, United States
Recruiting
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8400632 - North Ohio Heart Center
| Sandusky, Ohio, 44870, United States
Recruiting
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8400700 - Mercy Saint Vincent Medical Center
| Toledo, Ohio, 43608, United States
Recruiting
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8401164 - University of Toledo Medical Center
| Toledo, Ohio, 43614, United States
Recruiting
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8400639 - Genesis Health Care System
| Zanesville, Ohio, 43701, United States
Recruiting
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8400504 - Integris Baptist Medical Center
| Oklahoma City, Oklahoma, 73112, United States
Recruiting
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8400936 - South Oklahoma Heart Research
| Oklahoma City, Oklahoma, 73135, United States
Recruiting
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8400664 - Oklahoma Heart Institute
| Tulsa, Oklahoma, 74104, United States
Recruiting
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8401042 - Abington Medical Specialists
| Abington, Pennsylvania, 19001, United States
Completed
8400595 - Lehigh Valley Hospital
| Allentown, Pennsylvania, 18103, United States
Completed
8400608 - Holy Spirit Cardiology
| Camp Hill, Pennsylvania, 17001, United States
Active, not recruiting
8400872 - Chambersburg Hospital
| Chambersburg, Pennsylvania, 17201, United States
Recruiting
Use Central Contact
8400577 - Doylestown Cardiology Associates
| Doylestown, Pennsylvania, 18901, United States
Active, not recruiting
8400324 - Milton Hershey Medical Center
| Hershey, Pennsylvania, 17033, United States
Recruiting
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8400344 - Lancaster General Hospital
| Lancaster, Pennsylvania, 17604, United States
Completed
8400746 - Penn Presbyterian Medical Center
| Philadelphia, Pennsylvania, 19104, United States
Recruiting
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8400718 - V.A. Pittsburgh Healthcare System
| Pittsburgh, Pennsylvania, 15240, United States
Recruiting
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8400570 - Advanced Cardiology Specialists
| Scranton, Pennsylvania, 18508, United States
Recruiting
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8401179 - Reading Hospital
| West Reading, Pennsylvania, 19611, United States
Completed
8400794 - Geisinger Wyoming Valley
| Wilkes-Barre, Pennsylvania, 18711, United States
Active, not recruiting
8400811 - Rhode Island Hospital
| Providence, Rhode Island, 02903, United States
Completed
8400591 - AnMed Health Medical Center
| Anderson, South Carolina, 29621, United States
Recruiting
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8401171 - Greenville Hospital System
| Greenville, South Carolina, 29605, United States
Recruiting
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8401055 - Upstate Cardiology, PA
| Greenville, South Carolina, 29607, United States
Recruiting
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8400496 - Advanced Cardiology Associates
| Greenwood, South Carolina, 29646, United States
Recruiting
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8400582 - Carolina Heart Specialists
| Lancaster, South Carolina, 29720, United States
Active, not recruiting
8400320 - Black Hills Cardiovascular Research
| Rapid City, South Dakota, 57701, United States
Recruiting
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8400854 - The Chattanooga Heart Institute
| Chattanooga, Tennessee, 37404, United States
Active, not recruiting
8400500 - Tennova Health Care - Turkey Creek Medical Center
| Knoxville, Tennessee, 37934, United States
Recruiting
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8400760 - V.A. Medical Center - Memphis
| Memphis, Tennessee, 38104, United States
Recruiting
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8400873 - Baptist Clinical Research Institute
| Memphis, Tennessee, 38120, United States
Recruiting
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8400801 - Centennial Medical Center
| Nashville, Tennessee, 37203, United States
Completed
8400735 - Parkway Cardiology Associates, PC
| Oak Ridge, Tennessee, 37830, United States
Recruiting
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8400551 - Cardiovascular Research of Knoxville
| Powell, Tennessee, 37849, United States
Recruiting
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8400805 - PharmaTex Research
| Amarillo, Texas, 79016, United States
Recruiting
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8400482 - Amarillo Heart Clinical Research Institute
| Amarillo, Texas, 79106, United States
Recruiting
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8400485 - V.A. North Texas Health Care System
| Dallas, Texas, 75216, United States
Recruiting
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8400911 - Brooke Army Medical Center
| Fort Sam Houston, Texas, 78234-6200, United States
Active, not recruiting
8401231 - Revival Research Institute
| McKinney, Texas, 75069, United States
Recruiting
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8400881 - North Texas Research Associates
| McKinney, Texas, 75071, United States
Completed
8400921 - Mission Research Institute, LLC
| New Braunfels, Texas, 78130, United States
Recruiting
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8400890 - Revival Research Institute, LLC
| Sherman, Texas, 75092, United States
Recruiting
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8401176 - Methodist Sugar Land Hospital
| Sugar Land, Texas, 77479, United States
Active, not recruiting
8401128 - Hillcrest Family Health Center
| Waco, Texas, 76710-4023, United States
Recruiting
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8400515 - Wichita Falls Heart Clinic
| Wichita Falls, Texas, 76301, United States
Recruiting
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8401064 - Inova Fairfax Hospital
| Falls Church, Virginia, 22042-3300, United States
Recruiting
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8400502 - Stroobants Cardiovascular Center
| Lynchburg, Virginia, 24501, United States
Completed
8400601 - McGuire Research Institute
| Richmond, Virginia, 23249, United States
Recruiting
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8400759 - Winchester Cardiology and Vascular Medicine
| Winchester, Virginia, 22601, United States
Recruiting
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8400751 - Providence Everett Medical Center
| Everett, Washington, 98201, United States
Active, not recruiting
8400628 - Multicare Health System
| Puyallup, Washington, 98372, United States
Active, not recruiting
8400863 - Swedish Medical Center - Providence Campus
| Seattle, Washington, 98122, United States
Completed
8400503 - The Heart and Vascular Center / Holy Family Memorial
| Manitowoc, Wisconsin, 54220, United States
Recruiting
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8400358 - Aspirus Research Institute
| Wausau, Wisconsin, 54401, United States
Completed
0320069 - Hospital Italiano Regional del Sur
| Bahía Blanca, B8001HXM, Argentina
Recruiting
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0320020 - Clinica Privada
| Buenos Aires, 1722, Argentina
Completed
0320025 - Fundación Sanatorio Güemes
| Ciudad Autonoma Buenos Aires, 1413, Argentina
Recruiting
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0320041 - Clinica y Maternidad Suizo Argentina (CyMSA)
| Ciudad Autónoma Buenos Aires, 1118, Argentina
Active, not recruiting
0320019 - Hospital Británico de Buenos Aires
| Ciudad Autónoma Buenos Aires, 1280, Argentina
Recruiting
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0320029 - Instituto Cardiovascular de Buenos Aires
| Ciudad Autónoma Buenos Aires, 1428, Argentina
Recruiting
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0320034 - Clinica Adventista Belgrano
| Ciudad Autónoma Buenos Aires, 1430, Argentina
Recruiting
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0320033 - Corporacion Medica de San Martin
| Ciudad Autónoma Buenos Aires, 4071, Argentina
Recruiting
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0320013 - Hospital Municipal de Coronel Suárez
| Coronel Suárez, 7540, Argentina
Recruiting
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0320040 - Instituto de Cardiología de Corrientes
| Corrientes, 3400, Argentina
Recruiting
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0320015 - Clinica Chutro S.R.L.
| Córdoba, 5000, Argentina
Recruiting
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0320063 - Clinica Romagosa
| Córdoba, 5000, Argentina
Recruiting
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0320023 - Clínica Privada del Prado
| Córdoba, X5000AAX, Argentina
Recruiting
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0320012 - Sanatorio Allende
| Córdoba, X5000, Argentina
Recruiting
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0320036 - Hospital Italiano
| Córdoba, X5000, Argentina
Recruiting
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0320026 - Clínica Colombo
| Córdoba, X5002AOQ, Argentina
Recruiting
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0320039 - Santatorio Parque S.A.
| Córdoba, X5006IKK, Argentina
Recruiting
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0320022 - Hospital El Cruce
| Florencio Varela, 1888, Argentina
Recruiting
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0320014 - Hospital Italiano La Plata
| La Plata, B1897, Argentina
Recruiting
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0320016 - Sanatorio Modelo Quilmes
| Quilmes, 1878, Argentina
Recruiting
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0320044 - Instituto Medico de la Fundacion de Estudios Clínicos
| Rosario, 2000, Argentina
Recruiting
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0320017 - Entidades Vinculadas al Sanatorio Parque
| Rosario, S2000, Argentina
Recruiting
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0320071 - Hospital Provincial del Centenario
| Rosario, S2000, Argentina
Recruiting
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0320070 - Hospital Papa Francisco
| Salta, 4400, Argentina
Recruiting
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0320073 - Instituto Medico De Alta Complejidad - IMAC
| Salta, 4401, Argentina
Recruiting
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0320027 - Estudios Clínicos de los Arroyos
| San Nicolás, 2900, Argentina
Recruiting
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0320021 - Sanatorio Medico de Diagnostico y Tratamiento S.A.
| Santa Fe, 3000, Argentina
Recruiting
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0320038 - Sanatorio Mayo Privado S.A.
| Santa Fe, 3000, Argentina
Recruiting
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0320032 - Hospital Dr. Jose Maria Cullen
| Santa Fe, S3000, Argentina
Recruiting
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0320067 - Sanatorio Santa Rosa
| Santa Rosa, P3600, Argentina
Recruiting
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0320037 - Centro Privado de Cardiologia (CPC)
| Tucuman, 4000, Argentina
Recruiting
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0320054 - Clínica Privada de Especialidades Médicas de Villa María
| Villa María, 5901, Argentina
Recruiting
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0360087 - Campbelltown Hospital
| Campbelltown, New South Wales, 2560, Australia
Completed
0360069 - Liverpool Hospital
| Liverpool, New South Wales, 2170, Australia
Recruiting
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0360070 - Royal North Shore Hospital
| St. Leonards, New South Wales, 2065, Australia
Recruiting
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0360071 - Wollongong Hospital
| Wollongong, New South Wales, 2500, Australia
Recruiting
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0360063 - Cairns Base Hospital
| Cairns, Queensland, 4870, Australia
Recruiting
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0360062 - The Prince Charles Hospital
| Chermside, Queensland, 4032, Australia
Recruiting
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0360061 - Royal Brisbane Hospital
| Herston, Queensland, 4029, Australia
Recruiting
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0360060 - Gold Coast Hospital
| Southport, Queensland, 4215, Australia
Recruiting
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0360057 - Royal Adelaide Hospital
| Adelaide, South Australia, 5000, Australia
Recruiting
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0360032 - Flinders Medical Centre
| Bedford Park, South Australia, 5042, Australia
Recruiting
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0360055 - Queen Elizabeth Hospital
| Woodville South, South Australia, 5011, Australia
Recruiting
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0360084 - Royal Hobart Hospital
| Hobart, Tazmania, 7001, Australia
Recruiting
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0360092 - Monash Medical Centre
| Clayton, Victoria, 3168, Australia
Recruiting
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0360036 - The Northern Hospital
| Epping, Victoria, 3076, Australia
Recruiting
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0360096 - Peninsula Health
| Frankston, Victoria, 3199, Australia
Recruiting
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0360076 - Geelong Hospital
| Geelong, Victoria, 3320, Australia
Recruiting
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0360081 - Peninsula Heart Centre
| Langwarrin, Victoria, 3910, Australia
Recruiting
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0360073 - The Alfred Hospital
| Melbourne, Victoria, 3004, Australia
Recruiting
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0360080 - Fiona Stanley Hospital
| Murdoch, Western Australia, 6150, Australia
Recruiting
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0360059 - Royal Perth Hospital
| Perth, Western Australia, 6000, Australia
Recruiting
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0360072 - John Hunter Hospital
| New Lambton Heights, 2305, Australia
Recruiting
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0400035 - Landeskrankenhaus Feldkirch
| Feldkirch, 6800, Austria
Recruiting
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0400020 - LKH-Universität Hospital Graz
| Graz, 8036, Austria
Recruiting
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0400028 - Medizinische Universitaet Innsbruck - Universitaetsklinik für Innere Medizin
| Innsbruck, 6020, Austria
Recruiting
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0400034 - Klinikum Klagenfurt am Wörthersee
| Klagenfurt, 9020, Austria
Recruiting
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0400031 - Universitatsklinik fuer Innere Medizin II, Kardiol
| Salzburg, 5020, Austria